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PANS and PANDAS: New Understanding of an Underappreciated Cause of Chronic Illness

The Cutting Edge of Health and Wellness Today
Friday, February 19, at 2 PM Pacific

PANS and PANDAS: New Understanding of an Underappreciated Cause of Chronic Illness

Today, I am delighted to be joined by Amy Joy Smith, a Nurse Practitioner working at Pacific Frontier Medical, who has extensive experience working with complex chronic illness and a special interest in, and knowledge of PANS and PANDAS. While these names sound cuddly, they reflect a severe autoimmune response to an infection which has behavioral and neurological symptoms in both children and adults. Please join us for this important discussion about another under appreciated cause for chronic illness.
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Fluoride Danger to Children

SUNDAY APRIL 19, 2015:
DR. BILL HIRZY IN SANTA ROSA

William J. Hirzy, PhD will speak on fluoride danger to children.

Dr. Bill Hirzy (2015). Photo courtesy of Ellen Connett.

Dr. Bill Hirzy (2015). Photo courtesy of Ellen HIrzy.

Dr. Bill Hirzy, longtime top scientist for EPA Toxics Risk Assessment, will discuss the risks of fluoridated water to our children, followed by a Q & A session during which you can get answers to your questions direct from Dr. Hirzy.

Board Certified local physician Dr. April Hurley will be on hand in the lobby, before and after the presentation, to answer questions about fluoridated water from a medical viewpoint. You are invited to bring your friends and your questions.

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Optimal Health, Detoxification and Autism: A Conversation with Sidney Baker, MD

The Cutting Edge of Health and Wellness Today
Friday, April 17, at 2 PM Pacific

Optimal Health, Detoxification and Autism: A Conversation with Sidney Baker, MD

Today I will be joined by Dr. Sidney Baker, who has pioneered the understanding of the biochemical factors that lead to Autism and continues to provide the cutting-edge research into that condition. Dr. Baker’s grasp of chronic illness and how to approach it has been taught to countless physicians, enable them to provide better medical care for their patients.

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To Vaccinate or Not To Vaccinate: That is the Question!

The Cutting Edge of Health and Wellness Today
Friday, April 10, at 2 PM Pacific

To Vaccinate or Not To Vaccinate: That is the Question!

I will be joined by Dr. Joel Friedman to tackle the highly controversial topic of vaccinations. We will include the medical issues and the political issues for what we hope we be a fascinating discussion.

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FOR SCIENTISTS AT UC SAN DIEGO, THE EFFORT TO CONQUER AUTISM IS PERSONAL

Published in Triton, a UC San Diego Alumni Publication

By Scott LaFee
Scott LaFee is a public information officer at UC San Diego Health Sciences.

Heart disease and cancer kill. Chronic conditions like diabetes and arthritis plague millions. Alzheimer’s disease robs the elderly of their memories. But none are more terrifying than autism, which afflicts children and whose symptoms, seeming to appear without warning between the ages of two and three, can dramatically erase a child’s previous development and personality. ..

“Autism has a different kind of history,” says Laura Schreibman, Ph.D., distinguished professor emeritus of psychology who founded the groundbreaking Autism Intervention Research Program at UC San Diego in 1984. “For example, cancer never started off with parents being blamed. People got defensive. We know a lot about cancer, but relatively little about autism, which can result in some very strange or wrong-headed ideas. It’s sad, confusing and unfortunate . . . But I’ve never felt there was a better career for me.”
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ROBERT NAVIAUX

Robert NaviauxRobert Naviaux, M.D. ’86, Ph.D., is a relative newcomer to autism research.

A professor in the departments of Medicine, Pediatrics and Pathology, Naviaux is a highly regarded authority on mitochondria—the tiny power plants in all cells, whose dysfunction can result in an alarming array of metabolic diseases.

For decades, Naviaux and colleagues have pioneered genetic research in mitochondrial conditions. Some are well-known afflictions, such as diabetes, but others are not. Leigh’s disease, for example, is a rare inherited disorder that typically strikes without warning in a child’s first year of life, triggering seizures and rapid development regression. Patients rarely survive to adolescence.

Naviaux got seriously involved in autism research after being invited to a meeting of autism scientists. He listened, pondered and soon had the glimmerings of a new hypothesis. Different from classical forms of mitochondrial diseases, which are solely genetic, Naviaux concluded that autism was the result of multiple converging causes: genetic, environmental and a phenomenon dubbed the “cell danger response” (CDR).

The CDR hypothesis posits that when genes and environmental factors interact adversely, cells that feel threatened or become damaged react defensively. Their protective membranes stiffen. Internal metabolic processes change, most notably those involving mitochondria. Communications with other cells are dramatically reduced.

“Cells behave like countries at war,” Naviaux said. “When a threat begins, they harden their borders. They don’t trust their neighbors. But without constant communication with the outside, cells begin to function differently. In the case of neurons, it might be by making fewer or too many connections. One way to look at this related to autism is this: When cells stop talking to each other, children stop talking.”

Naviaux’s work pushes the limits of the prevailing autism paradigm, but he insists it is actually complementary. Autism results from genetics, environmental factors and dysfunctional metabolic processes.

In the last two years, he has published papers showing that when CDR is tamped down, allowing cells to restore normal communications and functions, autism-like symptoms in a mouse model are reversed.

The particular remedy uses a century-old drug for treating sleeping sickness. While its beneficial effects are temporary and adverse side effects make it unsuitable for long-term use, Naviaux thinks it could lead to new insights and therapies not yet imagined.

“We can only be observers and ask questions of nature. We can use the tools of the scientific method to test new ideas. We must have the courage to follow where the data leads us without bias.”

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From Eric Gordon, MD at Gordon Medical:

Gordon Medical  has just completed collecting the blood and urine samples on 40 patients with CFIDS/ME and 40 controls for a new study. In this study Dr Naviaux will apply the same technology he used in his study of autism to define the activation state of the cell danger response (CDR) in people with CFIDS/ME compared to people without symptoms. Treatment options will depend on the results and our ability to fund the next step in research. Treatments that are new require significant investment in not just the science but also in fulfilling governmental regulations designed to protect patients. We are hoping once we have our preliminary results back to begin raising money to pay for the next steps. Look for an upcoming post where we talk about CDR and metabolomics.

(The results are now in, the study is under review, and is expected to be published in fall of 2016. We are now raising funds for a replication study starting June 2016. See more at the website below. All sizes of donations are gratefully accepted.  Editor- 6/2/2016)

FIND OUT MORE ABOUT CDR AND METABOLOMICS AT GORDON MEDICAL RESEARCH CENTER.

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The Autism Epidemic: Understanding the Problems and Exciting New Treatments

Fridays at 2 PM Pacific Time
The Cutting Edge of Health and Wellness Today

The Autism Epidemic: Understanding the Problems and Exciting New Treatments

We will be discussing the spectrum of Autism which has now reached epidemic proportions. We now understand more about the causes for these diverse neurological conditions (which range from severe autism to Asperger’s Syndrome to ADHD) which allows us to provide valuable treatments. This will include our presentation about how NAET can make a big difference for many of these unfortunate children.

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ILADEF’s Pioneer Award to be given to a “Ray of Hope” Charles Ray Jones

Dr. Charles ray Jones MD, Pediatric Lyme DiseaseEach year, the International Lyme and Associated Diseases Educational Foundation (ILADEF) hosts a gala charity dinner to raise funds to support its Physician Training Program, Lyme Basics Course and other educational and training programs presented regionally and internationally. As part of the annual event, ILADEF honors a professional for his or her dedication to the advancement of the diagnosis and treatment of Lyme and other tick-borne illnesses.

This year, ILADEF will present the Pioneer Award to Charles “Ray” Jones, MD, the pediatrician who has been a Ray of Hope to thousands of children and their parents who struggle with the consequences of Lyme and other associated diseases. [Read more…]

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Whole Families with Lyme Disease

Elizabeth Large, NDElizabeth Large ND

This summer I spent 10 days in Pennsylvania and Connecticut on a mission to learn how two well known Lyme literate doctors treat pediatric Lyme disease. This preceptorship is made possible by an ILADS scholarship for those wanting to expand their knowledge in treating Lyme disease. The first three days were spent with Dr. Ann Corson (see a slideshow of Dr. Corson’s practice philosophy) who practices in a town barely making the map in rural Pennsylvania. Dr. Corson is an integrative doctor who treats both adults and children. She has incorporated a well rounded natural approach as well as using antibiotics as needed.  I was impressed at her advanced knowledge in natural medicine and her open-mindedness to

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Children at Risk for Lyme Disease

Elizabeth Large, NDBy Elizabeth Large, ND

Children are being misdiagnosed too frequently when they actually have Chronic Lyme Disease (CLD) or Tick Borne Disease (TBD). It is very important that parents, teachers, school administrators, school health professionals, pediatricians, mental health professionals and family members learn to understand the signs and symptoms of Lyme Disease. It is an epidemic and children are at high risk for contracting TBD. We need to identify both acute and chronic, persistent TBD. Acute infection is defined as infection for less than a year and easily treated with 6-12 weeks of antibiotics depending on the symptoms present. If a Bull’s Eye rash does occur then it is diagnostic of LD. Unfortunately only 15-30% of the time a Bull’s Eye rash occurs and other types of rash can present and not only around the tick bite site. The chronic form of CLD can be devastating and difficult to eradicate. It impacts all body systems especially the immune system, hormonal system and nervous system. The body begins to respond inappropriately creating further symptoms that can be painful and debilitating.

The primary take home message with children is that their symptoms can be subtle and easily written off as growing pains or increased emotional sensitivity until there is frank disability. Then they lose their normal childhood of playing with friends, participating in school activities, and other recreation outside of school. They lose the energy to lead normal lives. They become too sick.

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