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UCLA study suggests iron is at core of Alzheimer’s disease

Findings challenge conventional thinking about possible causes of disorder

By Mark Wheeler/ Originally published August 20, 2013

Alzheimer’s disease has proven to be a difficult enemy to defeat. After all, aging is the No. 1 risk factor for the disorder, and there’s no stopping that.

Most researchers believe the disease is caused by one of two proteins, one called tau, the other beta-amyloid. As we age, most scientists say, these proteins either disrupt signaling between neurons or simply kill them.

Now, a new UCLA study suggests a third possible cause: iron accumulation.

[Read more…]

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Chelation therapy in TACT: Daring to challenge dogma (and suspend disbelief)

By Eric J Topol MD
Director, Scripps Translational Science Institute
The Gary and Mary West Chair of Innovative Medicine
Chief Academic Officer, Scripps Health
La Jolla, CA

Originally posted at theheart.org on May 26,2013

Although suffering from significant imperfections, the TACT trial is a daring step toward a better understanding of how chelation therapy might affect heart disease. It seemed like a crazy notion in 2003—when the NIH invested $31 million to fund the research—but the consistent and notable reduction of a spectrum of clinical end points indicates that maybe something important—and controversial—is happening.

I’d like to review with you one of the most controversial trials in cardiovascular medicine that has been published in a long time: the TACT trial of over 1700 patients who had a prior myocardial infarction and then were getting chelation therapy.

The chelation therapy was given over 30 weeks, every week. It wasn’t just EDTA but also a mixture of various vitamins, potentially what you could consider antioxidants, that were added to the solution. It was given for 30 weeks consecutively, with another series of infusions given several weeks after that. And this was conducted at various sites. It took from 2003 to 2011—eight years—before it was completed.

Read the rest of this transcript or listen to Dr. Topol discuss the TACT trial…….

Look for upcoming articles by Gordon Medical practitioners on chelation as practiced at GMA.