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Catching Up with Dr. Elizabeth Large, N.D.

By Carolyn B. Welcome, PA-C

Dr. Elizabeth Large divides her time between GMA’s main office in Santa Rosa and its new waterfront location in San Rafael. Among the many tools in her toolbox, this naturopathic physician offers expertise in Methyl Genetic Nutrition Analysis (MGNA), a program that provides in-depth interpretation of data from 23andMe genetic testing. This method has allowed her to home in on her patients’ individual needs.  Dr. Large’s toolbox also includes Chinese and Western plant-based treatments, Low Dose Immunotherapy (LDI),* oral and intravenous antibiotics, IV therapy and hormones.

“Natural medicine is not one size fits all,” she notes.

Eric Gordon, MD and Elizabeth Large, ND at GMA - Maggie Perkins 2017

Eric Gordon, MD and Elizabeth Large, ND at GMA – Maggie Perkins 2017

Thanks to the information given by MGNA, Dr. Large is seeing fast and quite amazing results in patients who have had health problems for most of their lives.

“When you see a lot of variants in one area – histamines, for example,” she explains, “it might help to explain unresolved issues.” [Read more…]

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Don’t miss Encore Day at The Chronic Lyme Disease Summit 2

If you’re just hearing about it, there’s still time to gain free access to all of the expert talks! The Chronic Lyme Disease Summit 2 began on June 19th, when Wayne Anderson spoke, and since then many have learned from the expert wisdom so important to protocols that could radically improve the life of someone with Lyme disease.

What you could learn from these experts:
Symptoms (common and rare!)
Diagnosis and testing
Practical at-home health tips
Healing protocol explanations
And more!

1. Register immediately to see the rest of the FREE talks (in case you missed Wayne’s talk on the 19th,  it is included on Encore Day!)

Chronic Lyme Disease Summit 2 [Read more…]

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Google has a new app that can map air quality street by street

Google has been working on a new app that will map air quality street by street. Currently only available with info on Oakland, but the plan is to expand over time. Check out the interactive map. It looks  like some of the info could be generalized, like the increase in levels on major streets and highways.

We’ve been mapping air quality with Street View cars since 2014. Today, with our partners EDF and Aclima, we’re announcing the results of this effort for…
BLOG.GOOGLE
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Join Wayne Anderson, ND FREE on Monday to learn about Lyme disease!

Online FREE from
June 19-26, 2017

The Chronic Lyme Disease Summit 2 starts on June 19th, and tens of thousands will learn from the expert protocols that could radically improve the life of someone with Lyme disease.

Will you be there? I will be speaking on June 19 (Day One), so be sure to get registered now! I will discuss the different types of Borrelia, the Renaissance of Lyme disease treatment, and challenge versus treatment protocols. You can also purchase the full Summit to watch at your own pace. See the link below to find a package that works best for you.

Chronic Lyme Disease Summit 2 [Read more…]

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Researchers Studying Century-Old Drug in Potential New Approach to Autism

Excerpts from article originally posted May 26, 2017 | Scott LaFee and Heather Buschman, PhD in Newsroom

Robert Naviaux, MD PhDIn a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

“The purpose of CDR is to help protect the cell and jump-start the healing process,” said Naviaux, by essentially causing the cell to harden its membranes, cease interaction with neighbors and withdraw within itself until the danger has passed.

“But sometimes CDR gets stuck,” Naviaux said. “This prevents completion of the natural healing cycle and can permanently alter the way the cell responds to the world. When this happens, cells behave as if they are still injured or in imminent danger, even though the original cause of the injury or threat has passed.”

At the molecular level, cellular homeostasis or equilibrium is altered, creating an abnormal cellular response that leads to chronic disease. “When this happens during early child development,” said Naviaux, “it causes autism and many other chronic childhood disorders.”

Suramin works by inhibiting the signaling function of adenosine triphosphate (ATP), a nucleotide or small molecule produced by cellular mitochondria and released from the cell as a danger signal. When CDR is activated, the effect of extracellular ATP is similar to a warning siren that never stops. Suramin inhibits the binding of ATP and similar molecules to key purinergic receptors, according to Naviaux. It silences the siren, “signaling the cellular war is over, the danger has passed and cells can return to ‘peacetime’ jobs like normal neurodevelopment, growth and healing.”

Robert Naviaux, MD, PhD

All five boys who received the suramin infusion displayed improvements in language and social behavior, restricted or repetitive behaviors and coping skills. Assessment of improvements was based upon observational examinations and interviews using standardized tests and questionnaires, such as the Autism Diagnostic Observation Schedule, 2nd edition (ADOS-2), the Expressive One Word Picture Vocabulary Testing (EOWPWT), the Aberrant Behavior Checklist (ABC), the Autism Treatment Evaluation Checklist (ATEC), the Repetitive Behavior Questionnaire (RBQ) and the Clinical Global Impression (CGI) questionnaire. To minimize misinterpretation of natural day-to-day variations in symptoms, parents were asked to mark a symptom as changed in the 6-week CGI only if the symptom lasted for at least one week.

Read full article

Low-dose suramin in autism spectrum disorder: a small, phase I/II, randomized clinical trial

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Disaster Preparation During Older Americans Month

Our local Red Cross contact sent us the following information to get us ready for anything the summer may bring:

With all the rain leading to stupendous plant growth after years of drought, the Sonoma County Emergency Coordinator’s office is planning for what could be devastating fires, like the ones that devoured 20% of Lake County last year. You can get alerts on your phone (phone call, email or text), computer, or tablet (email) from SoCo Alerts, and you can also download the FEMA Mobile Disaster App (See below).

View in FEMA Multimedia Library

Read Transcript

May is Older Americans Month (sorry we are late!) and a great time to ensure you or any members of your household prepare for emergencies.

The first step is identifying what you, or older (or disabled) adults in your household may need to be prepared. Evaluate those needs, include them in your emergency plan, and add any necessary items to your emergency supply kit. The Ready Campaign recommends seniors consider the following measures: [Read more…]

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U.K. patients describe Myalgic Encephalomyelitis (ME) or (ME/CFS)

*Often called chronic fatigue syndrome (CFS) or ME/CFS


Video by M.E. Action

Patients like these are why Dr. Gordon began research into chronic illness. Find out about our Science in Service of Humanity metabolomics research in CFS/ME. Read our published study, “Metabolic Features of Chronic Fatigue Syndrome,” watch for the next study to be published in the fall of 2017, sign up to participate in new research as a patient or a healthy control, and donate to support the work.

Evidence that CFS truly does deserve all three elements of its name has accumulated over the years but a definitive diagnostic test has remained elusive. Until, perhaps, now. For in this week’s Proceedings of the National Academy of Sciences Robert Naviaux of the University of California, San Diego, and his colleagues published evidence that the metabolisms of those diagnosed with CFS are all changing in the same way. Their data suggest it is this cellular response to CFS-triggering traumas, and not the way the response is set in motion, which should define the illness. They also show that this response produces a chemical signal that might be used for diagnosis.

The Economist

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Elizabeth Large Featured in Press Democrat Article on Lyme Disease

Lucia Montiel, 9, uses a wheelchair to move around her Sonoma coast home since being diagnosed with Lyme disease (John Burgess/The Press Democrat)

Lucia Montiel, 9, uses a wheelchair to move around her Sonoma coast home since being diagnosed with Lyme disease (John Burgess/The Press Democrat)

Lyme disease leaves victims frustrated, searching for answers

Excerpted from an article by MARTIN ESPINOZA
THE PRESS DEMOCRAT | May 18, 2017

Treating these infections is like working in the dark,” said Large, adding that ticks can cause multiple infections. “You’re looking to find the light switch. Hopefully, the more you treat, you start to get a clearer picture of the infections the patient has.

Although tick activity is high in the spring and early summer, ticks are active yearlong, [Read more…]

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“Look of Lyme” Video Channel Launch at Under Our Skin

Look of Lyme
From Under Our Skin

What Does Your Lyme Look Like?

Look of Lyme is a new initiative by the makers of UNDER OUR SKIN to bring your personal stories of suffering and courage into the limelight. While the Internet and social media have exploded with personal videos, there is no place that serves as a repository and archive of the ever changing and growing landscape of Lyme disease. Look of Lyme changes that, offering a way to make the personal political by harnessing the power of crowdsourcing and media. Our individual stories create a collective story that cannot be dismissed! Also, as we begin to develop a third film in the UNDER OUR SKIN collection, Look of Lyme is a way we can screen for possible film subjects. After receiving your videos and possibly editing them for brevity, consistency and branding, we’ll present them on a new YouTube channel accessible to millions worldwide.

Go to the Look of Lyme webpage to get guidlines on how to film and submit your video.

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Eric Gordon and Nafysa Parpia to Speak at American Academy of Ozonotherapy

2017 AAO Annual Meeting

From the AAO website: What Is Ozone Therapy? Ozonotherapy is the use of medical grade ozone, a highly reactive form of pure oxygen, to create a curative response in the body. The body has the potential to renew and regenerate itself. When it becomes sick it is because this potential has been blocked. The reactive properties of ozone stimulate the body to remove many of these impediments thus allowing the body to do what it does best – heal itself. [Read more…]